Identification of a Mutation in the Bacillus subtilis S -Adenosylmethionine Synthetase Gene That Results in Derepression of S-Box Gene Expression
نویسندگان
چکیده
منابع مشابه
Identification of a mutation in the Bacillus subtilis S-adenosylmethionine synthetase gene that results in derepression of S-box gene expression.
Genes in the S-box family are regulated by binding of S-adenosylmethionine (SAM) to the 5' region of the mRNA of the regulated gene. SAM binding was previously shown to promote a rearrangement of the RNA structure that results in premature termination of transcription in vitro and repression of expression of the downstream coding sequence. The S-box RNA element therefore acts as a SAM-binding r...
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The s regulon of Bacillus subtilis is composed of genes encoding proteins for flagellar synthesis, motility, and chemotaxis. Concurrent analyses of s protein levels and flagellin mRNA demonstrate that sigD expression and s activity are tightly coupled during growth in both complex and minimal media, although they exhibit different patterns of expression. We therefore used the s-dependent flagel...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2006
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.188.10.3674-3681.2006